Mannitol Glycerol Urea. Glimepiride; Pioglitazone: Moderate Thiazide diuretics can decrease insulin sensitivity thereby leading to glucose intolerance and hyperglycemia. Calcium; Vitamin D: Moderate Dose adjustment of vitamin D or vitamin D analogs may be necessary during coadministration with thiazide diuretics. Combination diuretic treatment in severe heart failure: a randomized controlled trial. Ertugliflozin; Sitagliptin: Moderate Thiazide diuretics can decrease insulin sensitivity thereby leading to glucose intolerance and hyperglycemia. Thiazide diuretics do not contain the N4-aromatic amine or the N1-substituent which are present in sulfonamide antibiotics. Linagliptin; Metformin: Moderate Certain drugs, such as thiazide diuretics, tend to produce hyperglycemia and may lead to loss of glycemic control. This can be therapeutically advantageous, but lower dosages of each agent should be used. Morphine: Moderate Monitor for decreased diuretic efficacy and additive orthostatic hypotension when a thiazide diuretic is administered with morphine.
- Chlorthalidone (Oral Route) Precautions Mayo Clinic
- Chlorthalidone (PIM )
- Chlorthalidone Dosage & Rx Info Uses, Side Effects
- Chlorthalidone Indications
dosing for Hygroton, Thalitone (chlorthalidone), frequency-based adverse to gout or chronic renal failure; risk can be increased with doses ≥25 mg (in.
Video: Chlorthalidone renal dosing Chlorthalidone Tablet - Drug Information
Heart failure guidelines suggest a lower initial dose of to 25 mg PO once daily and Use chlorthalidone with caution in patients with severe renal disease. exchangeable sodium, glomerular filtration rate, and renal plasma flow. Although chlorthalidone produces dose-related reductions in serum potassium levels.
Patients with pre-existing hypovolemia or hypotension should have their condition corrected before diuretics such as chlorthalidone are initiated. Hydralazine; Isosorbide Dinitrate, ISDN: Moderate Concomitant use of nitrates with other antihypertensive agents can cause additive hypotensive effects.
Chlorthalidone (Oral Route) Precautions Mayo Clinic
Dextromethorphan; Guaifenesin; Phenylephrine: Moderate The cardiovascular effects of sympathomimetics may reduce the antihypertensive effects produced by diuretics. Therefore, clinicians should monitor serum magnesium concentrations periodically in patients taking a PPI and diuretics concomitantly. Alprostadil: Minor The concomitant use of systemic alprostadil injection and antihypertensive agents, such as thiazide diuretics, may cause additive hypotension.
Video: Chlorthalidone renal dosing Dose adjustment in renal and hepatic failure
Belladonna; Opium: Moderate Monitor for decreased diuretic efficacy and additive orthostatic hypotension when thiazide diuretics are administered with opium.
Chlorthalidone Dosage & Rx Info Uses, Side Effects
Chlorthalidone for poorly controlled hypertension in chronic kidney disease: chlorthalidone was added to existing medications in a dose of 25 mg/day, Hypertension, Renal/diagnosis; Hypertension, Renal/drug therapy*. Chlorthalidone prescription and dosage sizes information for physicians and healthcare Indications for Chlorthalidone: Edema Renal or hepatic impairment.
Initiation of thiazide diuretics under these circumstances can produce life-threatening situations such as cardiac arrhythmias, hypotension, or seizures.
Clozapine: Moderate Caution is advisable during concurrent use of clozapine and thiazide diuretics as concurrent use may increase the risk and severity of hypotension. Yohimbine: Moderate Yohimbine can increase blood pressure and therefore can antagonize the therapeutic action of antihypertensive agents. Porfimer is a light-activated drug used in photodynamic therapy; all patients treated with porfimer will be photosensitive.
Chlorpheniramine; Dextromethorphan; Phenylephrine: Moderate The cardiovascular effects of sympathomimetics may reduce the antihypertensive effects produced by diuretics.
Chlorthalidone renal dosing
Isosorbide Dinitrate, ISDN: Moderate Concomitant use of nitrates with other antihypertensive agents can cause additive hypotensive effects.
It was reported that only 8 of the 19 patients achieved total body weight reduction. Phenylephrine; Promethazine: Moderate The cardiovascular effects of sympathomimetics may reduce the antihypertensive effects produced by diuretics. Tubocurarine: Moderate Concomitant administration of hydrochlorothiazide to patients receiving nondepolarizing neuromuscular blockers e.
Electrolyte imbalances may occur while on these diuretics, which may in turn predispose patients to the cardiac effects of halofantrine.